Technical Considerations of Phosphorous-32 Bremsstrahlung SPECT Imaging after Radioembolization of Hepatic Tumors: A Clinical Assessment with a Review of Imaging Parameters

Pirayesh, Elahe and Amoui, Mahasti and Akhlaghpoor, Shahram and Assadi, Majid (2014) Technical Considerations of Phosphorous-32 Bremsstrahlung SPECT Imaging after Radioembolization of Hepatic Tumors: A Clinical Assessment with a Review of Imaging Parameters. Hindawi Publishing Corporation.

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Abstract

Background. Bremsstrahlung (BS) imaging during radioembolization (RE) confirms the deposition of radiotracer in hepatic/ extrahepatic tumors. The aimof this study is to demonstrate 32P images and to optimize the imaging parameters. Materials and Methods. Thirty-nine patientswith variable types of hepatic tumors, treatedwith the intra-arterial injection of 32P,were included. All patients underwent BS SPECT imaging 24–72 h after tracer administration, using lowenergy high resolution (LEHR) (18 patients) or medium energy general purpose (MEGP) (21 patients) collimators. A grading scale from1 to 4 was used to express the compatibility of the 32P images with those obtained from CT/MRI. Results. Although the image quality obtained with theMEGP collimator was visually and quantitatively better thanwith theLEHR(76%concordance score versus 71%, resp.), there was no statistically significant difference between them. Conclusion.The MEGP collimator is the first choice for BS SPECT imaging. However, if the collimator change is time consuming (as in a busy center) or an MEGP collimator is not available, the LEHR collimator could be practical with acceptable images, especially in a SPECT study. In addition, BS imaging is a useful method to confirm the proper distribution of radiotherapeutic agents and has good correlation with anatomical findings.

Item Type: Article
Additional Information: indexer:samaneh vafadar
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicin
Depositing User: Unnamed user with username karvarz1
Date Deposited: 19 Dec 2015 18:38
Last Modified: 19 Dec 2015 18:38
URI: http://eprints.bpums.ac.ir/id/eprint/4220

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