Surrogacy as a good option for treatment of repeated implantation failure: a case series

Aflatoonian, Nastaran and Eftekhar, Maryam and Aflatoonian, Behrooz and Rahmani, Elham (2013) Surrogacy as a good option for treatment of repeated implantation failure: a case series. Iran J Reprod Med., 11 (1). pp. 77-80.


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Background: Repeated implantation failure (RIF) is defined as pregnancy failure after two to six times with at least ten high grade embryo transfer to uterus. A variety of causes have been anticipated for RIF, including anatomical, autoimmune, genetics, endocrine and thrombotic anomalies. Factors responsible for RIF have important implication regarding treatment however in many couples a perfect cause cannot be found. Cases: In these case series, we reported nine couples with RIF that after investigation no definitive etiology was found for RIF and empirical therapy by heparin, aspirin and or immunotherapy was not effective. In these cases we recommended transfer of embryos to surrogate uterus. Nine patients were studied and six of them developed a normal pregnancy (pregnancy rate=66.66%). Conclusion: This study showed that surrogacy is a good option for treatment of RIF.

Item Type: Article
Additional Information: indexer:samaneh vafadar
Uncontrolled Keywords: Repeated implantation failure, Surrogacy, In vitro fertilization, Pregnancy rate.
Subjects: WO Surgery
Divisions: Faculty of Medicin
Depositing User: Unnamed user with username karvarz1
Date Deposited: 19 Dec 2015 18:39
Last Modified: 11 Jul 2017 09:13

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