Fard Esfahani, Armaghan and Chavoshi, Maryam and Noorani, Mohammad Hadi and Assadi, Majid (2010) Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report. JOURNAL OF MEDICAL CASE REPORTS, 4 (3).
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Abstract
Introduction: The diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes. Here, we describe the case of a patient with an ectopic adrenocorticotropic hormone-producing bronchial carcinoid tumor diagnosed preoperatively using technetium-99m-labeled octreotide acetate scintigraphy. Case presentation: A 29-year-old Asian man presented to our hospital with the typical clinical features of Cushing’s syndrome, which he had had for a duration of 18 months. The results of a biochemical evaluation revealed he had adrenocorticotropic hormone-dependent Cushing’s syndrome. The results of a spiral abdominal computed tomography scan showed he had bilateral adrenal hypertrophy. A magnetic resonance image of the patient’s brain showed he had a normal hypophysis. Whole body technetium-99m-labeled octreotide acetate scintigraphy was performed to check for the presence of an ectopic adrenocorticotropic hormone-producing tumor. The scan results showed a small focal increase in uptake in the lower lobe of our patient’s right lung, just above his diaphragm. A spiral chest computed tomography scan also revealed a small non-specific lesion in the same region. A transthoracic biopsy was then performed. Pathological evaluation confirmed the diagnosis of a carcinoid tumor, of the adrenocorticotropic hormone-producing type. After surgical removal, the patient’s symptoms resolved and significant clinical improvement was achieved. Conclusions: This case report shows that technetium-99m-labeled octreotide acetate scintigraphy can effectively detect an ectopic adrenocorticotropic hormone-producing bronchial carcinoid.
| Item Type: | Article |
|---|---|
| Additional Information: | indexer:samaneh vafadar |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicin |
| Depositing User: | Unnamed user with username karvarz1 |
| Date Deposited: | 19 Dec 2015 18:39 |
| Last Modified: | 19 Dec 2015 18:39 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/4255 |
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