Javadi, Hamid and Jallalat, Sara and Shahriar, Semnani and Mehdi, Mogharrabi and iraj, Nabipour and Seyed Masoud, Tabib and Moloud, Abbaszadeh and majid, Assadi (2013) The association of increased stomach wall radiotracer uptake with prolonged use of Omeprazole capsules on myocardial perfusion imaging (MPI) using 99mTc-sestamibi SPECT. Nuclear Medicine Review, 16 (2). pp. 91-94.
Full text not available from this repository.Abstract
Myocardial perfusion imaging (MPI) is widely used in routine practice for diagnosis and risk stratification of coronary artery disease (CAD). Intense curvilinear activity in the stomach wall of a patient was seen on MPI raw data. This phenomenon was completely dissimilar to the familiar intraluminal gastric reflux of sestamibi. This observed activity could have resulted in false-positive or false-negative artifacts — and inaccurate diagnosis — of the inferior wall of the left ventricle after MPI processing. On further exploration, the current researchers found Myocardial perfusion imaging (MPI) with exercise or pharmacological stress, either with thallium-201 (201Tl) or technetium-99m (99mTc)-sestamibi, is widely used for preparation of diagnostic and prognostic information regarding patients with proved or possible coronary artery disease (CAD) and it facilitates the accurate management of CAD patients [1]. However, with present myocardial radiotracers, such as 99mTc-sestamibi, rather high extra-cardiac activity is usually seen, which is mostly associated with physiologic hepatobiliary or renal excretion [2]. In contrast, there are limited reports suggesting possible non-physiologic reasons for these visceral uptakes, and occasionally, indicating different underlying pathologies [2]. Indeed, accidental pathological fi ndings during myocardial perfusion imaging are not scarce and cautious examination of the full fi eld of image acquisition has been useful in identifying these accidental fi ndings [3–5]. Alternatively, most efforts concentrate on dissolving these interfering abdominal activities without attention to the clinical importance of such fi ndings [6, 7]. On the MPI raw data of one such patient, intense curvilinear activity in the stomach wall was evident. This phenomenon was completely dissimilar to the familiar intraluminal gastric
| Item Type: | Article |
|---|---|
| Additional Information: | indexer: mehran zakizadeh |
| Uncontrolled Keywords: | 99mTc-sestamibi cardiac SPECT, myocardial perfusion imaging, gastric wall, proton pump inhibitors |
| Divisions: | Faculty of Medicin |
| Depositing User: | Unnamed user with username karvarz1 |
| Date Deposited: | 17 Jul 2016 03:11 |
| Last Modified: | 17 Jul 2016 03:11 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/4456 |
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