Prevalence and Trends of Transfusion- Transmissible Viral Infections among Blood Donors in South of Iran: An Eleven-Year Retrospective Study

Farshadpour, Fatemeh and Taherkhani, Reza and Tajbakhsh, Saeed and Gholizadeh Tangestani, Marziyeh and Hajiani, Gholamreza and Sharifi, Nasrin and Taherkhani, Sakineh and Nejadbolkheyr, Abdolreza (2016) Prevalence and Trends of Transfusion- Transmissible Viral Infections among Blood Donors in South of Iran: An Eleven-Year Retrospective Study. PLOS ONE.

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Abstract

Background Blood transfusion is considered a potential risk factor for transmission of life-threatening viral infections, including HIV, HCV and HBV infections. This study was performed to find out the prevalence and trends of these infections among blood donors in Southern Iran. Methods The blood donor data recorded in twelve regional blood transfusion centers from 2004 to 2014 were analyzed in an anonymous way with respect to the results of serological screening for HBV, HCV, and HIV infections. Overall, 293454 donors were screened for viral infections. Results Most of the donors were male, married, aged between 20–40 years, educated, and regular donors. The overall seroprevalence rates of HBV, HCV and HIV were 0.15%, 0.1% and 0.004%, respectively. The highest seroprevalence was found for HBV, followed by HCV and HIV. These infections were more prevalent in male, low educated and first time donors. The highest HCV seroprevalence was observed among donors aged 20 to 40 years, while HBV seroprevalence increased with age. The seroprevalence rates of HBV and HCV from 2004 to 2014 showed significant decreasing trends from 0.460% to 0.060% (P < 0.001) and 0.329% to 0.045% (P < 0.001), respectively. Whereas HIV infection had a slight but not significant decline from 0.0173%in 2004 to 0.0028%in 2014 (P = 0.087).

Item Type: Article
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicin > Department of Infectious Diseases
Depositing User: یلدا کمال گلپاشا
Date Deposited: 17 Oct 2016 06:29
Last Modified: 17 Oct 2016 06:29
URI: http://eprints.bpums.ac.ir/id/eprint/5376

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