Hepatitis E Virus Seroprevalence Among Blood Donors in Bushehr, South of Iran.

Naeimi, B and Mazloom Kalimani, F and Pourfatolah, AA and Azimzadeh, M and Mankhian, A and Akbarzadeh, S and Hajiani, G and Kooshesh, F and Khamisipour, G (2015) Hepatitis E Virus Seroprevalence Among Blood Donors in Bushehr, South of Iran. Hepnat Mo.

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Abstract

BACKGROUND: Although so far several studies have determined the hepatitis E virus (HEV) prevalence in some parts of Iran, no data exists regarding the HEV seroprevalence in Bushehr province as the southernmost point in Iran yet. OBJECTIVES: The aim of this study was to evaluate the seroprevalence of anti-HEV IgG among the blood donors in Bushehr. PATIENTS AND METHODS: A total of 628 blood donor samples were collected from September to October 2013, after obtaining informed written consents, and analyzed for the presence of anti-HEV IgG using commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. All the samples were tested by two ELISA kits and evaluated for liver function test. RESULTS: Overall, 105 (16.7%) blood samples were positive for HEV-specific-IgG antibodies, while 523 (83.8%) were negative. The presence of anti-HEV IgG was not associated with gender; however, it was correlated with age. It was indicated that the anti-HEV prevalence increases by age and there was a significant difference between the age groups regarding HEV seropositivity. CONCLUSIONS: High HEV seroprevalence (16.7%) was observed among the blood donors in Bushehr province. It appears that exposure to HEV increases with age; although, more people should be examined.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Faculty of Medicin > Department of Surgery
Depositing User: سپیده مقدسی
Date Deposited: 02 Jul 2018 06:48
Last Modified: 02 Jul 2018 06:48
URI: http://eprints.bpums.ac.ir/id/eprint/6009

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