Hepatitis E Virus Seroprevalence Among Blood Donors in Bushehr, South of Iran

Naeimi, Behrouz and Mazloom Kalimani, Farnaz and Pourfatolah, Ali Akbar and Azimzadeh, Masoud and Mankhian, Alireza and Akbarzadeh, Samad and Hajiani, Gholamreza and Kooshesh, Faramarz and Khamisipour, Gholamreza (2015) Hepatitis E Virus Seroprevalence Among Blood Donors in Bushehr, South of Iran. Naeimi B et al.


Download (73kB) | Preview


Background: Although so far several studies have determined the hepatitis E virus (HEV) prevalence in some parts of Iran, no data exists regarding the HEV seroprevalence in Bushehr province as the southernmost point in Iran yet. Objectives: The aim of this study was to evaluate the seroprevalence of anti-HEV IgG among the blood donors in Bushehr. Patients and Methods: A total of 628 blood donor samples were collected from September to October 2013, after obtaining informed written consents, and analyzed for the presence of anti-HEV IgG using commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. All the samples were tested by two ELISA kits and evaluated for liver function test. Results: Overall, 105 (16.7%) blood samples were positive for HEV-specific-IgG antibodies, while 523 (83.8%) were negative. The presence of anti-HEV IgG was not associated with gender; however, it was correlated with age. It was indicated that the anti-HEV prevalence increases by age and there was a significant difference between the age groups regarding HEV seropositivity. Conclusions: High HEV seroprevalence (16.7%) was observed among the blood donors in Bushehr province. It appears that exposure to HEV increases with age; although, more people should be examined.

Item Type: Article
Subjects: QU Biochemistry
Divisions: Faculty of Medicin > Department of Biochemistry
Depositing User: سپیده مقدسی
Date Deposited: 03 Jul 2018 08:16
Last Modified: 03 Jul 2018 08:16
URI: http://eprints.bpums.ac.ir/id/eprint/6217

Actions (login required)

View Item View Item