Ostovar, Afshin and Assadi, Mahsan and Vahdat, Katayoun and Nabipour, Iraj and Javadi, Hamid and Eftekhari, Mohammad and Assadi, Majid (2013) A Pooled Analysis of Diagnostic Value of 99mTc-Ubiquicidin (UBI) Scintigraphy in Detection of an Infectious Process. Clin Nucl Med, 38. pp. 413-416.
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Abstract
Purpose: Although the data are promising fromlimited studies with technetium- 99m ubiquicidin (99mTc-UBI) scintigraphy in detection of infection in humans, these studies have had a limited sample size. This study was conducted to provide a systematic review and meta-analysis of the reported diagnostic accuracy of 99mTc-UBI scintigraphy in detection of an infectious process. Materials and Methods: The PubMed/MEDLINE,Web of Science, EMBASE, and Google Scholar literature databases were systematically searched to find the relevant human studies on 99mTc-UBI scintigraphy. For each eligible study, the truepositive, false-positive, true-negative, and false-negative findings at 99mTc-UBI scintigraphy were recorded, and the overall statistical parameters were acquired. Result: Ten studies carried out from 2004 to 2010 were included in the analysis. The pooled data sensitivity was 94.5 % and with a 95% confidence interval of 91.2%Y96.8%. The pooled specificity was still as high as about 92.7%. The range of reported specificity was from 80% to 100%. The overall accuracy was 93.7% (95% CI: 91.2%Y95.7%). Conclusion: The study demonstrated that 99mTc-UBI scintigraphy can be used to identify an infectious process with admirable accuracy in early views; however, further investigations are recommended.
| Item Type: | Article |
|---|---|
| Subjects: | WC Communicable Diseases |
| Divisions: | Faculty of Medicin |
| Depositing User: | زهرا صفایی |
| Date Deposited: | 03 Jul 2018 08:29 |
| Last Modified: | 03 Jul 2018 08:29 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/6326 |
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