Effect of fentanyl versus buprenorphine on the pupil size in phacoemulsification cataract surgery

Motamed, Niloofar and Najafi Anaraki, Abdolreza and Akrami, Abbas and Seydali, Elham (2012) Effect of fentanyl versus buprenorphine on the pupil size in phacoemulsification cataract surgery. Saudi Journal of Anaesthesia, 6 (3). pp. 268-272.

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Abstract

Background: Despite several recent innovations in phacoemulsification surgery, importance of pupil diameter in this surgery is becoming more evident. Purpose: To compare the effect of opioid agonist (fentanyl) versus opioid agonist–antagonist (buprenorphine) on pupil diameter in cataract surgery and to choose the best opioid in high-risk phacoemulsification surgery. Methods: In this randomized double-blinded clinical trial, 60 patients who were candidates for elective phacoemulsification surgery were randomly divided into two equal groups: experimental (buprenorphine, 0.3 μg/kg) and control (fentanyl, 1 μg/kg). Pupil diameter was measured preinjection and at several times postinjection. Blood pressure was recorded at several intervals, as well as shivering, nausea and vomiting, and recovery time. Results: Mean (SD) recovery time was significantly less in the control group (19.46±5.43) than in the experimental group (33.23±10.75) (P<0.0001). The constriction effect (ie, pupillary diameter in mm) was significantly lower in the experimental group (0.53±0.45) than in the control group (1.06±0.52) (P=0.0001). The percentages of constriction effect in experimentaland control groups were 7.68% and 15.07%, respectively. The eye was two times more constricted in the control group in comparison with the experimental group after induction of anesthesia. Conclusion: Buprenorphine is a better solution to decrease pupil constriction in comparison with fentanylinhigh-risk phacoemulsification surgery.

Item Type: Article
Subjects: WW Ophthalmology
Divisions: Faculty of Medicin > Department of Social Medicine
Depositing User: محسن زارعی
Date Deposited: 02 Jul 2018 09:00
Last Modified: 02 Jul 2018 09:00
URI: http://eprints.bpums.ac.ir/id/eprint/6327

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