Raeisi, A and Ostovar, A and Vahdat, K and Rezaei, P and Darabi, H and Moshtaghi, D and Nabipour, I (2016) Association of serum uric acid with high-sensitivity C-reactive protein in postmenopausal women. Climacteric, 20 (1). pp. 44-48.
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Abstract
Objectives: To explore the independent correlation between serum uric acid and low-grade inflammation (measured by high-sensitivity C-reactive protein, hs-CRP) in postmenopausal women. Methods: A total of 378 healthy Iranian postmenopausal women were randomly selected in a population- based study. Circulating hs-CRP levels were measured by highly specific enzyme-linked immunosorbent assay method and an enzymatic calorimetric method was used to measure serum levels of uric acid. Pearson correlation coefficient, multiple linear regression and logistic regression models were used to analyze the association between uric acid and hs-CRP levels. Results: A statistically significant correlation was seen between serum levels of uric acid and log-transformed circulating hs-CRP (r¼0.25, p<0.001). After adjustment for age and cardiovascular risk factors (according to NCEP ATP III criteria), circulating hs-CRP levels were significantly associated with serum uric acid levels (b ¼ 0.20, p<0.001). After adjustment for age and cardiovascular risk factors, hs-CRP levels �3 mg/l were significantly associated with higher uric acid levels (odds ratio ¼1.52, 95% confidence interval 1.18–1.96). Conclusion: Higher serum uric acid levels were positively and independently associated with circulating hs-CRP in healthy postmenopausal women.
| Item Type: | Article |
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| Subjects: | WP Gynecology |
| Divisions: | Faculty of Medicin |
| Depositing User: | زهرا صفایی |
| Date Deposited: | 03 Jul 2018 08:29 |
| Last Modified: | 03 Jul 2018 08:29 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/6328 |
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