Relationship between Body Mass Index, Waistto- Hip Ratio, and Serum Lipid Concentrations and Thyroid-Stimulating Hormone in the Euthyroid Adult Population

Rahbar, Ali Reza and Kalantarhormozi, Mohamadreza and Izadi, Fatemeh and Arkia, Elham and Rashidi, Marzie and Pourbehi, Fatemeh and Daneshifard, Farzaneh and Rahbar, Amin (2017) Relationship between Body Mass Index, Waistto- Hip Ratio, and Serum Lipid Concentrations and Thyroid-Stimulating Hormone in the Euthyroid Adult Population. Iranian journal of medical sciences., 42 (3). pp. 301-305.

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Abstract

The aim of this cross-sectional study was to investigate the relationship between body mass index (BMI), waist-to-hip ratio, and lipid parameters and serum thyroid-stimulating hormone (TSH) levels in healthy euthyroid individuals. This cross-sectional study was conducted between June 1st and July 20th, 2013, at Bushehr University of Medical Sciences. One hundred forty euthyroid individuals were divided into 2 groups: a high-TSH group (TSH between 2.0 and 5.5 mIU/L, n=67) and a low-TSH group (TSH between 0.3 and 2.0 mIU/L, n=73). After overnight fast, total cholesterol, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), TSH, thyroxine (T4), and triiodothyronine (T3) were measured. Height and weight were measured with a stadiometer, and BMI was calculated as weight in kilograms divided by the square of height in meters. Waistto- hip ratio was determined as waist circumference divided by hip circumference. The simple independent t-test and a general linear model were used for statistical analysis. All statistical analyses were done using the SPSS, version 15, statistical software package. BMI and LDL-C were significantly higher in the high-TSH group than in the low-TSH group after adjustment for age, sex, calorie intake, total fat and carbohydrate intakes, and physical activity. No significant differences were found between the groups in TG, cholesterol, and HDL-C. The association between TSH levels andT4 was significant. Individuals with TSH levels at the upper limit of normality might be at risk of hypercholesterolemia and obesity.

Item Type: Article
Subjects: WB Practice of Medicine
Divisions: Faculty of Medicin
Depositing User: سپیده مقدسی
Date Deposited: 03 Jul 2018 08:32
Last Modified: 03 Jul 2018 08:32
URI: http://eprints.bpums.ac.ir/id/eprint/6544

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