Akbarzadeh, Samad and Taherkhani, Reza and Farshadpour, Fatemeh and Makvandi, Manoochehr and Rajabi Memari, Hamid and Samarbafzadeh, Ali Reza and Sharifi, Nasrin and Naeimi, Behrouz and Tajbakhsh, Saeed (2015) Cytokine Profiles and Cell Proliferation Responses to Truncated ORF2 Protein in Iranian Patients Recovered from Hepatitis E Infection. Journal of Tropical Medicine.
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Abstract
Background.The aim of this study was to evaluate hepatitis E virus (HEV) specific cellular immune responses to truncated ORF2 protein in Iranian patients recovered from HEV infection. Information about HEV-specific immune responses could be useful in finding an effective way for development of HEV vaccine. Methods. A truncated formof HEVORF2 protein containing amino acids 112-608 was used to stimulate peripheral blood mononuclear cells (PBMCs) separated from HEV-recovered and control groups. Finally, the levels of four cytokines, IFN-
| Item Type: | Article |
|---|---|
| Subjects: | QU Biochemistry |
| Divisions: | Faculty of Medicin > Department of Biochemistry |
| Depositing User: | زهرا صفایی |
| Date Deposited: | 03 Jul 2018 08:36 |
| Last Modified: | 03 Jul 2018 08:36 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/6669 |
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