Evaluation of Classic Wiskott Aldrich Syndrome with Mild Symptoms in Two Cousins: A Case Report

Shirkani, Afshin and Farrokhi, Shokrollah (2017) Evaluation of Classic Wiskott Aldrich Syndrome with Mild Symptoms in Two Cousins: A Case Report. Iranian Journal of Pediatrics, 27 (5). ISSN 2008-2142

[img]
Preview
Text
Shirkani.pdf

Download (805kB) | Preview

Abstract

Introduction: Wiskott–Aldrich syndrome (WAS) is characterized by microthrombocytopenia, eczema, recurrent infections, and an increased incidence of autoimmunity. Commonly, classicWAS is presented with severe clinical symptoms. Case Presentation:We report a new phenotype of classic Wiskott–Aldrich syndrome with mild symptoms in two cousins who were 7 years old. They had not severe infections or hemorrhage, in spite of having genetic mutation in WAS gene. The symptoms and infections of the patients responded to treatment with IVIG and antibiotics. Conclusions: This report is presenting a novel clinical phenotype of classicWAS with milder symptoms.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Faculty of Medicin > Department of Immunology and Allergy
Depositing User: محسن زارعی
Date Deposited: 02 Jul 2018 06:51
Last Modified: 02 Jul 2018 06:51
URI: http://eprints.bpums.ac.ir/id/eprint/6934

Actions (login required)

View Item View Item