Levofloxacin Resistance in Blood and Urine Culture Samples in Khalij Fars Hospital of Bushehr

Hadavand, Fahimeh and Vahdat, Katayoun and Yazdani, Sara and Motamed, Niloofar (2017) Levofloxacin Resistance in Blood and Urine Culture Samples in Khalij Fars Hospital of Bushehr. Iranian South Medical Journal, 20 (5). pp. 492-500. ISSN 1735-4374


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Background: Due to the broad-spectrum antimicrobial activity of Levofloxacin, it has been used widely around the world. Recently, levofloxacin-resistance reports have been published. In this study, we investigated resistance to levofloxacin in positive urine and blood culture samples in Persian Gulf hospital in Bushehr, Iran, during 2015-16. Materials and Methods: In this cross-sectional study, the selection criteria included all positive urine or blood culture samples in which the amount of the isolated pathogen colony counts were more than 105 . Culture samples were divided into three groups including sensitive, intermediate and resistant; based on bacterial growth around the discs. SPSS version 18.0 was used as the statistical analysis software, and a pvalue of less than 0.05 was considered statistically significant. Results: Culture samples consisted of samples of150 patients including 61 (%40.7) male and 89 (%59.3) female. Mean age of participants was 42.98 ± 29.25. Culture samples consisted of urine (% 50.7) and blood cultures (% 49.3). E.coli was the most common pathogen (% 46) and Klebsiella (% 16.7) was the second common pathogen in all cultures. Regarding the sensitivity to levofloxacin, 119 (% 79.3) samples were sensitive, 22 (% 14.7) cultures had intermediate sensitivity and 9 (%6) samples were resistant to levofloxacin. The only resistant pathogen was E.coli. Conclusion: This study showed that Levofloxacin has a reasonably high efficiency against most of the bacterial pathogens except for the E.coli that showed some resistance. Hence, this antibiotic can still be a considered as a good choice in the treatment of most infections except E.coli

Item Type: Article
Subjects: WC Communicable Diseases
Divisions: Faculty of Medicin > Department of Infectious Diseases
Depositing User: محسن زارعی
Date Deposited: 03 Jul 2018 02:21
Last Modified: 03 Jul 2018 02:21
URI: http://eprints.bpums.ac.ir/id/eprint/6945

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