Nasehi, Nima and Askarian, Roya and Askarian, Farahnaz and Ghorbanihaghjo, Amir and Argani, Hassan and Sanajou, Davoud and Ahmadi, Ravan and Rahtchizadeh, Nadereh (2018) Soluble Tumor Necrosis Factor Like Weak Inducer of Apoptosis and Vitamin D in Hemodialysis Patients: Relation to Carotid Intima-Media Thickness. Indian Journal of Clinical Biochemistry, 33 (3). pp. 297-303.
Full text not available from this repository.Abstract
Cardiovascular disease, as the leading cause of patient death with chronic kidney disease, could be predicted by carotid atherosclerosis. The aim of the present study was to evaluate a possible relationship between serum soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) and Vitamin D levels with mean right/left carotid intima-media thickness (cIMT), in the hemodialysis (HD) patients. In this cross-sectional study, serums were obtained from 50 stable chronic HD patients and 39 healthy controls. The serum levels of sTWEAK, Vitamin D, intact parathyroid hormone (iPTH) in both groups, and cIMT were determined in HD patients by standard methods. Serum levels of sTWEAK were higher [808.8 (521.6–5032.4) pg/ml vs. 664.4 (487.4–2955.8) pg/ml (p = 0.006)] and Vitamin D levels were lower [13.4 (2.5–153) ng/ml vs. 27.8 (18.4–59.0) ng/ml (p = 0.001)] in the hemodialysis patients than in the healthy control. No important correlation was found between sTWEAK Vitamin D levels (r = 0.010/p = 0.946), and mean right(r = −0.194/p = 0.178) and left (r = 0.061/p = 0.673) cIMT in the HD patients. Our study shows that sTWEAK levels are elevated in HD patients. This elevation has no association with the cIMT.
| Item Type: | Article |
|---|---|
| Subjects: | WJ Urogenital System |
| Divisions: | Faculty of Medicin > Department of Radiology |
| Depositing User: | محسن زارعی |
| Date Deposited: | 06 Oct 2018 10:42 |
| Last Modified: | 06 Oct 2018 10:42 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/7216 |
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