Ahmadi, Bahram and Rezaei-Matehkolaei, Ali and Khodavaisy, Sadegh and Alshahni, Mohamad Mahdi and Tamura, Takashi and Satoh, Kazuo and Abastabar, Mahdi and Shokoohi, Gholam Reza (2018) In vitro antifungal activity of novel triazole efinaconazole and five comparators against dermatophyte isolates. Antimicrobial Agents and Chemotherapy.
Full text not available from this repository.Abstract
The objective of this study was to assess the in vitro activity of the novel triazole antifungal drug, efinaconazole, and five comparators (luliconazole, lanoconazole, terbinafine, itraconazole, and fluconazole) against a large collection of Trichophyton interdigitale and Trichophyton rubrum clinical isolates. The geometric mean MICs were the lowest for luliconazole (0.0005 μg/ml), followed by lanoconazole (0.002 μg/ml), efinaconazole (0.007 μg/ml), terbinafine (0.011 μg/ml), itraconazole (0.095 μg/ml), and fluconazole (12.77 μg/ml). It appears that efinaconazole, lanoconazole, and luliconazole are promising candidates for the treatment of dermatophytosis due to T. interdigitale and T. rubrum.
| Item Type: | Article |
|---|---|
| Subjects: | QX Parasitology |
| Divisions: | Faculty of Medicin > Department of Microbiology |
| Depositing User: | زهرا صفایی |
| Date Deposited: | 07 Oct 2018 09:57 |
| Last Modified: | 07 Oct 2018 09:57 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/7223 |
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