Sensitivity to antibiotics of bacteria exposed to gamma radiation emitted from hot soils of the high background radiation areas of Ramsar, Northern Iran

Zarei, Samira and Tajbakhsh, Saeed and Mortazavi, Seyed Mohamad Javad and Taheri, Mohammad and Mortazavi, Seyed Ali Reza and Ranjbar, Sahar and Momeni, Fatemeh and Masoomi, Samaneh and Ansari, Leila and Movahedi, Mohammad Mehdi and Taeb, Shahram and Zarei, Sina and Haghani, Masoud (2017) Sensitivity to antibiotics of bacteria exposed to gamma radiation emitted from hot soils of the high background radiation areas of Ramsar, Northern Iran. International Journal of Occupational and Environmental Medicine, 8 (2). pp. 80-84.

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/28432369

Abstract

Background: Over the past several years our laboratories have investigated different aspects of the challenging issue of the alterations in bacterial susceptibility to antibiotics induced by physical stresses. Objective: To explore the bacterial susceptibility to antibiotics in samples of Salmonella enterica subsp. enterica serovar Typhimurium (S. typhimurium), Staphylococcus aureus, and Klebsiella pneumoniae after exposure to gamma radiation emitted from the soil samples taken from the high background radiation areas of Ramsar, northern Iran. Methods: Standard Kirby-Bauer test, which evaluates the size of the zone of inhibition as an indicator of the susceptibility of different bacteria to antibiotics, was used in this study. Results: The maximum alteration of the diameter of inhibition zone was found for K. pneumoniae when tested for ciprofloxacin. In this case, the mean diameter of no growth zone in non-irradiated control samples of K. pneumoniae was 20.3 (SD 0.6) mm; it was 14.7 (SD 0.6) mm in irradiated samples. On the other hand, the minimum changes in the diameter of inhibition zone were found for S. typhimurium and S. aureus when these bacteria were tested for nitrofurantoin and cephalexin, respectively. Conclusion: Gamma rays were capable of making significant alterations in bacterial susceptibility to antibiotics. It can be hypothesized that high levels of natural background radiation can induce adaptive phenomena that help microorganisms better cope with lethal effects of antibiotics.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Faculty of Medicin > Department of Microbiology
Depositing User: سپیده مقدسی
Date Deposited: 31 Dec 2018 08:39
Last Modified: 31 Dec 2018 08:39
URI: http://eprints.bpums.ac.ir/id/eprint/7391

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