Effects of intermittent fasting during ramadan on insulin-like growth factor-1, interleukin 2, and lipid profile in healthy muslims

Rahbar, Ali Reza and Safavi, Eisa and Rooholamini, Maryam and Jaafari, Fateme and Darvishi, Sadegh and Rahbar, Amin (2019) Effects of intermittent fasting during ramadan on insulin-like growth factor-1, interleukin 2, and lipid profile in healthy muslims. International Journal of Preventive Medicine, 10 (1).

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Abstract

Background: Insulin-like growth factor-1 (IGF-1) and interleukin-2 (IL-2) play an essential role in pathophysiology of several chronic diseases. As a stressor, fasting in Ramadan may increase inflammatory markers such as IGF-1 and IL-2 in Muslims. The aim of this before-after study was to investigate the effects of fasting in Ramadan on IGF-1 and IL-2 levels in individuals. Methods: In all, 34 men age 16-64 years were selected out of the overall number of individuals who were ready for fasting entirely throughout Ramadan. A sample of blood was drawn from the contributors before and after Ramadan, and plasma IGF-1, IL-2, total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were determined. To identify differences between the initial and final values of test results of the study for plasma IGF-1, IL-2, and lipid parameters, we used paired sample T-test. Results: Paired sample T-test illustrated a significant decrease in IGF-1 and IL-2 levels after Ramadan fasting compared to before Ramadan. The concentration of TG, cholesterol, and LDL-C levels underwent significant decreases over the period of the study. HDL-C levels did not change significantly during the study. A significant decrease in weight, waist circumferences, calorie, carbohydrate, and fat intake were observed in participants during Ramadan fasting. Conclusions: It is concluded that fasting in Ramadan independent of anthropometric measures attenuates inflammation and is beneficiary to health.

Item Type: Article
Subjects: WB Practice of Medicine
Divisions: Research Center > The Persian Gulf Tropical Medicine Research Center
Depositing User: محسن زارعی
Date Deposited: 17 Apr 2019 07:40
Last Modified: 17 Apr 2019 07:40
URI: http://eprints.bpums.ac.ir/id/eprint/7801

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