Zareifar, S and Shakibazad, N and Zekavat, O.R. and Bordbar, M and Shahriari,, M (2020) Successful treatment of refractory metastatic neuroblastoma with panobinostat in combination with chemotherapy agents and iodine-131-meta-iodobenzylguanidine therapy. Journal of Oncology Pharmacy Practice, 26 (2). pp. 481-486. ISSN 1078-1552
Full text not available from this repository.Abstract
Introduction: Neuroblastoma commonly required multimodal therapy containing surgery, chemotherapy, radiotherapy, and immunotherapy. Case report: In our case, who had refractory metastatic neuroblastoma, we use histone deacetylase inhibitor (panobinostat) in combination with chemotherapy agents and iodine-131-meta-iodobenzylguanidine (MIBG) therapy. Management and outcome: This approach leads to successfully treat the patient. MIBG scan and bone marrow examination after therapy revealed no evidence of tumor. Now, she underwent autologous transplantation six months ago and free of tumor. Conclusion: Panobinostat can cause apoptosis induction in refractory metastatic neuroblastoma in combination with MIBG therapy and chemotherapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | chemotherapy histone deacetylase inhibitor Neuroblastoma refractory |
| Subjects: | R Medicine > RX Homeopathy WH Hemic and Lymphatic System |
| Divisions: | Faculty of Medicin |
| Depositing User: | خدیجه شبانکاره |
| Date Deposited: | 22 Dec 2020 08:33 |
| Last Modified: | 22 Dec 2020 08:33 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/9082 |
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