Esmaeilzadeh, H. and Askarisarvestani, A. and Hosseini, N. and Samimi, S. and Shafiei, A. and Mahdaviani, S.A. and Eslami, N. and Chavoshzadeh, Z. and Fallahi, M. and Khakbazanfard, N. and Shabestari, M.S. and Aleyasin, S. and Nabavizadeh, S and Cheraghi, T. (2021) Document details - Adverse reactions in a large cohort of patients with inborn errors of immunity receiving intravenous immunoglobulin. Clinical Immunology, 230. ISSN 15216616
Full text not available from this repository.Abstract
Background: Intravenous immunoglobulins (IVIg) are the major treatment in inborn errors of immunity (IEI) disorders; However, IVIg infusions show some adverse effects. We aimed to assess the adverse reactions of IVIg infusions. Methods: Data of IVIg infusions in IEI patients were collected from 2011 to 2021. Totally, 363 IEI patients received IVIg regularly in Iran entered the study. The adverse reactions are classified regarding their severity and chronicity. Results: 22,667 IVIg infusions were performed in the study. 157 patients (43.2%) and 1349 (5.9%) infusions were associated with at least one type of adverse reaction. The highest rates of adverse reactions were seen in severe combined immunodeficiency. Myalgia, chills, headache, fever, and hypotension were the most frequent adverse effects of IVIg. Conclusion: The reactions affect almost half of the patients mainly in the first infusions which necessitate the close observation of IEI patients receiving IVIg
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Adverse reactionInborn errors of immunityIntravenous immunoglobulinsIranPrimary immunodeficiencies |
| Subjects: | A General Works (کلیات) > AC Collections. Series. Collected works A General Works (کلیات) > AC Collections. Series. Collected works |
| Divisions: | Faculty of Medicin > Department of Immunology and Allergy |
| Depositing User: | خدیجه شبانکاره |
| Date Deposited: | 27 Dec 2021 10:01 |
| Last Modified: | 27 Dec 2021 10:01 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/9452 |
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