Taherkhani, R and Farshadpour, F (2021) Molecular identification and clinical characteristics of mumps virus and human herpesviruses associated with aseptic meningitis in South of Iran. Indian Journal of Virology, 23 (4). pp. 666-673. ISSN 2347-3584
Full text not available from this repository.Abstract
Viral infections are the major etiological agent of aseptic meningitis; though, limited data exist on the prevalence and molecular epidemiology of viral pathogens responsible for the occurrence of aseptic meningitis in Iran. Therefore, this study aimed to elucidate the prevalence and clinical features of mumps virus and human herpesviruses associated with aseptic meningitis in the South of Iran. A total of 73 patients with aseptic meningitis were enrolled in this study. Cerebral spinal fluid (CSF) samples were tested for detection of HSV, CMV, VZV and mumps virus using nested PCR assay. Mumps virus, HSV-1 and VZV were found in 4 (5.5%), 4 (5.5%) and 3 (4.1%) of the CSF samples, respectively. The highest rates of mumps virus and HSV infections were observed in infants less than one year, and VZV was more prevalent in patients under 5 years of age. The majority of mumps virus and VZV infections were found among male patients, while HSV was more prevalent among female patients. The highest incidence of aseptic meningitis associated with mumps virus was observed in summer, while HSV and VZV were more prevalent during spring. Headache was the most common symptom in mumps meningitis. About HSV and VZV, the most predominant clinical symptom was fever. The results of this study indicate the importance of molecular assay in the diagnosis of etiological agents of aseptic meningitis. Prompt detection of viral pathogens provides a better chance of managing viral meningitis in health care settings.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Aseptic meningitis; Cytomegalovirus; Herpes simplex viruses; Iran; Mumps virus; Varicella zoster virus |
| Subjects: | WL Nervous system |
| Divisions: | Faculty of Medicin > Department of Microbiology |
| Depositing User: | خدیجه شبانکاره |
| Date Deposited: | 27 Dec 2021 09:54 |
| Last Modified: | 27 Dec 2021 09:54 |
| URI: | http://eprints.bpums.ac.ir/id/eprint/9489 |
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