Association of dietary acid load with metabolic syndrome in overweight and obese women

Tangestani, Hadith and Emamat, Hadi and Tavakoli, Atefeh and Ghalandari, Hamid and Keshavarz, Seyed Ali and Yekaninejad, Mir Saeed and Mirzaei, Khadijeh (2022) Association of dietary acid load with metabolic syndrome in overweight and obese women. International Journal for Vitamin and Nutrition Research. ISSN 0300-9831

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Background: There is increasing evidence supporting the association between dietary acid load and metabolic syndrome (MetS) components. However, to the best of our knowledge, there are rare and inconsistent studies to examine the association of dietary acid load and MetS score. The aim of this research was to assess dietary acid loads as measured by potential renal acid load (PRAL) in relation to MetS. Methods: The current study involved 246 overweight or obese women. Dietary assessment was performed using a validated 147-item food frequency questionnaire (FFQ). Remer’s equation was used to calculate PRAL score. MetS was defined as the National Cholesterol Education Program (NCEP)/Adult Treatment Panel ΙΙΙ (ATP). Multivariable logistic regression models were used to find the association between PRAL score and MetS. Results: The mean age and BMI of participants were 36.49±8.38 years old and 31.04±4.31 kg/m2, respectively. Overall, 32 percent of participants had MetS. According to the final model, although not statistically significant, there was a trend which suggested that being in the highest quartile of adherence to dietary acid load, evaluated by PRAL score, compared to the lowest quartile was associated with higher odds of MetS [(OR: 2.80; 95% CI: 0.95–8.26), (P=0.06)]. Conclusions: Our study shows a borderline non-significant association between PRAL and odds of MetS in overweight or obese women. However, definitive clarification of this relationship requires future intervention studies.

Item Type: Article
Subjects: WB Practice of Medicine
Divisions: Research Center > The Persian Gulf Tropical Medicine Research Center
Depositing User: خدیجه شبانکاره
Date Deposited: 09 Nov 2022 07:31
Last Modified: 09 Nov 2022 07:31

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